美时与Alvotech签署授权与商业化合作协议于美国及亚洲市场推动两项生物相似药

2026-10-05 20:56:09 网络阅读（70）
美时(1795-TW)今(21)日晚间召开重讯记者会，宣布与Alvotech(ALVO-US)签署策略授权与商业化合作协议，将于美国及主要亚洲市场共同推动Imfinzi(durvalumab)及Hemlibra(emicizumab)生物相似药候选药物AVT34及AVT87 。
美时说明，Imfinzi是一款用于治疗多种癌症的生物制剂，2025年全球销售额约61亿美元；Hemlibra则是一款用于A型血友病患者常规性预防治疗，可预防或降低出血事件发生频率的生物制剂，2025年全球销售额约48亿瑞士法郎，约58亿美元。
美国方面，美时将透过既有商业团队推动2项产品商业化，Alvotech则依非专属协议，保留两项产品于美国直接商业化的权利。另外，Alvotech将持续负责2项产品的开发、药证取得与维护，并作为产品在协议中所有市场的独家供应商。
亚洲部分，美时将取得8个市场的独家商业化权利，包括南韩、台湾、泰国、越南、菲律宾、新加坡、香港及马来西亚，并负责当地药证申请。
总经理Petar Vazharov表示，此次合作结合Alvotech生物相似药开发与制造能力、美时在美国及亚洲深厚的商业化经验与市场基础，将有效推动AVT34及AVT87未来在全球主要市场的商业化。此外，这2项候选药物将进一步拓展美时生物相似药产品在肿瘤及罕病领域的布局。
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