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解开百年分子镜像之谜 法日学者共获2026年诺贝尔化学奖

2026-10-07 19:53:52 网络 阅读(1)

瑞典皇家科学院宣布,2026年诺贝尔化学奖颁给法国学者卡甘(Henri B. Kagan)与日本学者硖合宪三,以表彰两人在「不对称有机合成中发现非线性效应与自动催化」的卓越贡献。两人将平分1200万瑞典克朗(约120万美元)的奖金。

解开百年分子镜像之谜 法日学者共获2026年诺贝尔化学奖

自然界中的许多分子(如胺基酸)存在像左右手般互为镜像的「对映体」结构。生命体仅选择使用其中一种镜像分子,这种「单一手性」(homochirality)的自发形成过程困扰了化学界逾一世纪。

卡甘于1986年率先发现非线性效应,能调控反应以大幅提升特定镜像分子的产率;硖合宪三则更进一步,成功开发出能自发且纯粹生成单一镜像分子的自动催化反应(Soai反应),在生物体外首次达成此一壮举。

诺贝尔化学委员会主席Heiner Linke赞赏表示:「卡甘与硖合宪三解答了单一手性如何自发产生的百年难题,他们开发的化学反应堪称壮观。」委员会指出,这项成果对新药开发、香料及新材料设计具有决定性影响。

科睿唯安科学资讯研究所研究分析主管David Pendlebury评述称:「今年的获奖成果展现了历经数十年展现的深远影响,提醒人们变革性的进展往往源自持续、由好奇心驱使的研究,基础科学发现的重要性可能需要多年才能被完全理解。」

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