天天财经-提供金融入门知识-投资理财技巧-2026年诺贝尔生理学或医学奖美德三大科学家凭借「光遗传学」成就获奖

2026年诺贝尔生理学或医学奖美德三大科学家凭借「光遗传学」成就获奖

2026-10-05 19:18:43 网络阅读（1）
2026年诺贝尔奖季节于10月5日正式揭幕，首先揭晓的是诺贝尔生理学或医学奖。瑞典卡罗琳斯卡学院诺贝尔委员会宣布，本届生医奖由美国史丹佛大学教授戴瑟沃夫(Karl Deisseroth)、德国柏林洪堡大学教授黑格曼(Peter Hegemann)以及德国维尔茨堡大学教授纳格尔(Georg Nagel)共同荣获。
2026年诺贝尔生理学或医学奖美德三大科学家凭借「光遗传学」成就获奖
三位学者因在「光感应离子通道」与「光遗传学」领域的开创性发现，平分总额1,200万瑞典克朗的奖金。
针对这项跨时代的突破，诺贝尔生理医学委员会主席史文宁森(Per Svenningsson)特别强调：「光遗传学提供了前所未有的机会，让我们能以过去梦寐以求的方式绘制大脑地图。」
卡罗琳斯卡学院诺贝尔委员会也在官方声明中赞扬，三位得主为现代神经科学奠定了全新里程碑，使研究人员能够精准调控活体大脑中个别神经细胞的活动，彻底揭开了大脑运作的神秘面纱。
这项突破源于黑格曼对单细胞衣藻趋光性的好奇探索。2000年代初期，黑格曼与纳格尔共同发现了单细胞绿藻表面一种特殊的光敏蛋白质「频道菱形藻蛋白」(channelrhodopsin)。当蓝光照射该蛋白质时，离子通道会瞬间开启并导入电荷、触发电脉冲，使细胞具备感光能力。
随后，戴瑟沃夫于2005年成功将该基因植入大鼠神经细胞中，并于2007年进一步在活体小鼠大脑中实现以光开关控制神经讯号。
诺贝尔委员会补充说明，光遗传学现已成为全球神经科学实验室的标准技术，能精准解析掌管记忆、情绪与行为的神经回路，对神经与精神疾病研究至关重要，临床上亦正尝试应用于恢复视障患者的视力。
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